Founded in Vigevano in 2017 as an innovative medtech start-up

Born to solve a problem that costs human lives

PoloPlasma was founded to address airborne microbiological contamination in hospitals and critical environments through scientifically validated cold plasma technology.

2017

Founded in Vigevano, Italy

2

Patents filed for the technology

TRL9

Validated prototype installed

Clinical field validation

24/7 testing in a real surgical theatre

OUR STORY

Da un problema urgente a una tecnologia brevettata

Four key milestones in eight years of research, development and field validation.

2017 — The beginning

The birth of PoloPlasma

After many years facing the long‑standing issue of hospital microbiological contamination, especially in operating rooms, and the ongoing problem of healthcare‑associated infections (HAI), at the end of 2017 PoloPlasma S.r.l. was founded as an innovative start‑up.

Together with several colleagues and friends, the idea took shape: to develop an automatic decontamination system capable of tackling this problem, based on a cold plasma process applied to ambient air, at low pressure and temperature, with a dynamic behavior differing between day and night and with a process that is technically effective, repeatable and safe.

Limited company founded

Innovative start‑up

Vigevano (PV)

Bicocca University — Physics

University of Milan — Microbiology

ISO 8 cleanroom

Pharmaceutical industry

2018–2020 — Research and development

First development with the university and first field experience

The initial development stemmed from a collaboration with the University of Milano‑Bicocca, Institute of Physics, and the University of Milan, Institute of Microbiology. This was followed by an initial validation in an ISO 8 pharmaceutical industrial cleanroom, with excellent results in combination with the existing ventilation system.

2021–2024 — Exploration and strategic focus

Experience in various industrial and pharmaceutical sectors

Several prototypes were built and used to explore three application areas: decontamination in the hospital‑healthcare sector, food preservation in modified‑atmosphere chambers and sterilization in pharmaceutical isolators and sterilizers for surgical instruments.

The experience gained led to concentrating all research on hospital decontamination in surgical theatres and on dry sterility, with the food sector being phased out.

The strategic decision to focus on hospital decontamination in operating rooms proved decisive for the development of PLASMAIR.

Multi‑sector prototypes
Pharmaceutical isolators
Focus: hospital healthcare

PLASMAIR — product name

2 registered patents

TRL9 prototype

Ce.Me.Di. Turin — Lifenet

CE marking — process underway

2024–2026 — Commercialization

PLASMAIR is born: TRL9 prototype installed at Ce.Me.Di. in Turin (Lifenet Group)

Through a collaboration between PoloPlasma and Ssprogetti, Futura Innovazione was founded, securing public funding for the development of the hospital project and for the Italian distribution of the product, which was given the name PLASMAIR.

The pre‑commercial TRL9 prototype was installed in a surgical theatre. Two patents were obtained covering the decontamination and sterilization processes, protecting the original process. The procedure to obtain CE marking was launched in order to begin commercialization.

The pre‑commercial TRL9 prototype was installed in a surgical theatre. Two patents were obtained covering the decontamination and sterilization processes, protecting the original process. The procedure to obtain CE marking was launched in order to begin commercialization.

The latest TRL9 prototype operated for 6 consecutive months, 24/7, in a non‑classified surgical theatre, achieving ISO 7 classification at the Ce.Me.Di. outpatient clinic in Turin, with a reduction of −85% in bacterial load and −50% in airborne particles.

COLLABORATIONS AND PARTNERSHIPS

The network that made PLASMAIR possible

SCIENTIFIC RESEARCH

University of Milano‑Bicocca — Institute of Physics

Development and characterization of the SDBD plasma reactor. Study of the reactive species generated and optimization of the air ionization process.

SCIENTIFIC RESEARCH

University of Milan — Microbiology

Microbiological validation of the process. Efficacy tests on bacteria, viruses and fungal spores under controlled laboratory and cleanroom conditions.

INDUSTRIAL PARTNERSHIP

Ssprogetti — Futura Innovazione

Creation of Futura Innovazione for the commercial development and Italian distribution of PLASMAIR. Public funding obtained for the hospital project.

CLINICAL VALIDATION

Ce.Me.Di. di Torino — Gruppo Lifenet

Site where the latest TRL9 prototype was installed in a controlled healthcare environment, used for continuous testing as clinical validation of the final product.

INDUSTRIAL VALIDATION

Pharmaceutical ISO 8 cleanroom

First field validation in a controlled pharmaceutical environment, with excellent results in combination with the existing mechanical ventilation (VMC) system.

Do you want to become an international distribution partner for PLASMAIR?

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Request a technical assessment of your HVAC infrastructure and contamination-control requirements. Our engineering team will evaluate the integration of PLASMAir technology within your existing ventilation systems.